Note that some minor differences exist between the analyses included in these synopses compared to the analyses presented in the corresponding publications. These differences arise because the information included here is based on analyses defined strictly according to the protocol (as required by international regulatory authorities), whereas the information presented in the corresponding publications are based on the scientific requirements of the ATAC Steering Committee (membership of the Steering Committee is described within the publications referenced). In all cases the differences between the analyses are of a small magnitude and the conclusions from them are the same.